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This list contains some of
the current research activities that are happening in New York
State. Should you wish further information on the research
project you should contact the program director. If you would
like to include your research on this list contact ASAP.
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Program Director
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Type of Grant / Project
Description
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David Perlman
Beth Israel Medical Center
New York
1st Ave at 16th St
New York, NY 10003
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NIDA Project Tuberculosis Screening
& Prevention in Active Users
We have documented a high prevalence of TB infection among
active New York City drug users (DU s), and a marked rise in
the prevalence with age and years of drug use, suggesting a
high average annual incidence of TB infection.
Nonetheless, we have demonstrated that with appropriate
program models, high rates of acceptance and adherence to
voluntary TB screening and preventive therapy can be achieved.
Date
Started: 30-Sep-94 Date
Ends: 31-Dec-02
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Nora Volkow
Brookhaven Science Assoc. - Brookhaven Lab
Brookhaven National Lab
Upton, NY 11973
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NIDA Project Studies in Cocaine
Abusers
No further information is available at this time.
Date
Started: 15-Sep-90 Date
Ends: 31-Aug-02
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Denise Kandel
Columbia University Health Sciences
OGC
New York, NY 10032
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NIDA Project Substance
Dependence/Abuse in the US Population
No further information is available at this time.
Date
Started: 30-Sep-94 Date
Ends: 31-Jan-01
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Frances Levin
Columbia University Health Sciences
OGC
New York, NY 10032
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NIDA Project Treatment of Cocaine
Abuse & Psychiatric Comorbidity
For most cocaine-dependent individuals, standard treatment
approaches have not been effective. Although a substantial
percentage of cocaine abusers have other psychiatric
conditions, knowledge about these groups and appropriate
interventions are inadequate. It has been hypothesized that
psychiatrically-impaired cocaine abusers may be
self-medicating their psychiatric symptoms with psychoactive
substances. Within this application, three cocaine-abusing
subpopulations will be evaluated: those with attention deficit
hyperactivity disorder (ADHD), those with schizophrenia, and
those with personality disorders.
Date
Started: 30-Sep-94 Date
Ends: 31-Aug-00
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Edward Nunes
Columbia University Health Sciences
OGC
New York, NY 10032
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NIDA Project Drug Abuse
Pharmacotherapy - Metholgic Initiatives
The applicant’s program of research is driven by two main
themes: 1) That pharmacotherapies may be developed by
considering the heterogeneity of drug addicted samples, and by
targeting interventions to specific subgroups; and 2) that the
Medications Development effort for cocaine abuse is in need of
improved methods for early Phase II trials in which
preliminary indications of efficacy are sought.
Date
Started: 1-Apr-96 Date
Ends: 31-Mar-01
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Henri Begleiter
Health Science Center at Brooklyn
450 Clarkson Ave.
New York, NY 11203
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NIAAA Project Brain
Dysfunction & Alcoholism
No further information is available at this time.
Date started 28-Feb-03 Date ends28-Feb-03
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Henri Begleiter
Health Science Center at Brooklyn
450 Clarkson Ave.
New York, NY 11203
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NIAAA Project Collaborative
Study on the Genetics of Alcoholism
No further information is available at this time.
Date started 31-Aug-04 Date ends31-Aug-04
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Mangai Natarajan
John Jay College of Criminal Justice
899 10th Ave.
New York, NY 10019
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NIDA Project Understanding Upper
Level Heroin Dealing in New York City
This is a competing continuation application for a ADAMHA
Scientist development Award. The continued support would
assist the candidate’s career by providing an opportunity to
continue in-depth investigations of upper-level heroin dealing
in New York City, using secondary analysis of extensive police
and court data from investigations designed to support the
prosecution of major heroin dealers. After conducting a pilot
study, of small and less complex cases of heroin dealers, the
candidate will analyze official documents relating to the
investigation and prosecution of the Pizza Connection case.
Date
Started: 30-Sep-95 Date
Ends: 29-Feb-00
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Elinore McCance-Katz
Montefiore Medical Center
Bronx
111 E. 210th St
New York, NY 10467
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NIDA Project Cocaine, Alcohol, &
Cocaethylene - Clinical Effects
One hypothesis regarding the high incidence of comorbid
cocaine and alcohol abuse is that cocaethylene, with its lack
of serotonin reuptake inhibition, alleviates acute abstinence
symptoms and dysphoria associated with binge cocaine use.
Cocaethylene may
be used as a tool to sort out the role of serontonin versus
dopamine in mediating the actions of disulfiram on cocaine
effects.
Date
Started: 20-Mar-96 Date
Ends: 31-Jul-03
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Bruce Johnson
National Development & Research Institutes, Inc.
New York, NY 10048
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NIDA Project Estimating Current Hard
Drug Users and Operatives
Accurate estimation of the number and characteristics of hard
drug abusers and operatives has long plagued policy makers and
treatment providers. The goal of this proposed research is to
refine a survey methodology that can accurately estimate the
size if the “hard-to-reach,” hidden population of hard
drug users who have used heroin, cocaine, and crack within the
last 30 days, and operatives in the drug trade (e.g., sellers,
go-betweens, and managers of shared consumption locales).
Date
Started: 1-Jul-96 Date
Ends: 30-Jun-00
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Marc Laruelle
New York State Psychiatric Institute
1051 Riverside Dr.
New York, NY 10032
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NIDA Project Neurobiology of
Cocaine-Induced Sensitization
The general aim of this proposal is to study with brain
imaging the neurochemical mechanisms underlying sensitization
to psychostimulants in humans.
Date
Started: 10-May-97 Date
Ends: 31-Mar-00
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Mary Kreek
Rockefeller University
66th & York Ave.
New York, NY 10021
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NIDA Project Addictive Drugs -
Pharmacology & Physiology
Research activities will continue to identify and study the
biological correlates of addictions, factors which affect
treatment outcome, and also, primarily, the molecular
neurological basis of addiction.
Date
Started: 1-Feb-78 Date
Ends: 31-Mar-03
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Mary Kreek
Rockefeller University
66th & York Ave.
New York, NY 10021
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NIDA Project Addictions: Genotypes,
Polymophisms & Function
No further information is available at this time.
Date
Started: 30-Sep-99 Date
Ends: 31-Aug-04
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Gerrard Connors
SUNY at Buffalo
Capen Hall
Buffalo, NY 14260
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NIAAA Project
Secondary Prevention of Alcohol Problems in Rural Areas
Problem drinking in rural areas is an important health
services issue, not because of the potential for such drinking
to create life-functioning problems, but because fewer
treatment services are available in rural areas. This research
endeavor is consistent with the long-term goal of identifying
interventions which can be efficiently and effectively
delivered to subgroups of rural problem drinkers, in this case
men and women. As such, the findings will have direct
relevance to the administration of health services to persons
with alcohol use problems.
Date started 31-Aug-01 Date ends31-Aug-01
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Michael Frone
SUNY at Buffalo
Capen Hall
Buffalo, NY 14260
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NIAAA Project Work, Alcohol
& School Performance
No further information is available at this time.
Date started 31-Aug-00 Date ends31-Aug-00
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Jerrold Winter
SUNY at Buffalo
Capen Hall
Buffalo, NY 14260
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NIDA Project Behavioral &
Pharmacological Analysis of Drugs of Abuse
Among the drugs of abuse, hallucinogens are perhaps unique in
that an understanding of their mechanisms of action will not
only ameliorate the burdens of illicit use but may also
provide a key to solving the puzzle of psychosis, another
major human affliction. The present investigations seek to
characterize and to distinguish indoleamine hallucinogens such
as LSD and phenethylamine hallucinogens as exemplified by DOM
in combined behavioral (drug-induced stimulus control) and
biochemical (radiolig and binding and second messenger)
studies.
Date
Started: 1-Jan-85 Date
Ends: 31-May-01
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Ronald Wood
University of Rochester
River Campus Sta.
Rochester, NY 14627
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NIDA Project Behavioral Pharmacology
of Abused Aerosols - Crack
Smoking of cocaine base (‘crack”) has emerged as a
significant substance abuse problem yet there have been
comparatively few attempts to model the physiological or
behavioral effects of inhaled cocaine base in animals. These
studies will have bearing on possible treatment strategies for
cardiovascular, pulmonary and/or behavioral consequences of
crack smoking in humans.;
Date
Started: 30-Sep-88 Date
Ends: 30-Jun-00
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Kenneth Tardiff
Weill Medical College of Cornell University
New York, NY 10021
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NIDA Project Fatal Consequences of
Cocaine & Opiate Use
We plan to continue our study of the fatal medical and
behavioral consequences of drug use, namely fatal injuries.
Continuing our long-established collaboration
with the New York City Medical Examiner (ME) we will
collect and analyze data from 1994-1997 on 2,800 acute drug
overdoses, 8,400 homicides, 2,600 suicides, and 6,000 other
fatal accidents. This sample, added to our current core data
base of an equal number of cases will allow us to analyze
40,000 cases of fatal injuries over 8 years. In addition, we
will use new sources of data that include medical examiner
autopsy reports for pathology of overdoses and routine HIV
test reports on all fatal injuries as well as district
attorney homicide investigation reports.
Date
Started: 30-Sep-90 Date
Ends: 30-Jun-00
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Research Page
